Abstract:
Introduction: Anemia is common medical problem in pregnancy in which the number of red 
blood cells or their oxygen carrying capacity is insufficient to meet physiologic needs. Though 
anemia in light of its magnitude and associated factors well studied, there is a paucity of research 
regarding maternal anemia and its association with perinatal out come at study area. .Therefore, 
this study aimed to investigate magnitude of the anemia, its associated factors and its relationship 
with perinatal outcome.
Methods and Materials: Facility based cross-sectional study was conducted among 405 
pregnant mothers admitted to deliveries in four public hospitals of Harar town and Dire Dawa 
administrative city. Systematic random sampling was used to select the study participants. The 
data were entered into Epi-data version 3.1 and exported to SPSS version 22 for analysis. 
Bivariate and multivariate analysis was done by using binary logistic regression. All variables 
with P<0.25 in bivariate analysis were included into final model and statistical significance was 
declared at P<0.05. 
Results: This study outlined that prevalence of anemia using the cut off level of 
Hemoglobin<11mg/dl (<33%of hematocrit) was 33.1% 95%CI= 28.4%, 37.8%).Of these sever, 
moderate and mild anemia accounts7.5%, 43.3% and 49.2% respectively. Being the rural 
residence(AOR=3.8,95%CI:1.815,7.946)},ANC(AOR=3.4,95%CI:1.341,8.791),Blood lose in 
pregnancy{(AOR=0.25,95%CI:0.066,0.964)},khatchewing{(AOR=3.0,95%CI:1.309,6.926).freq
uencyofmeals(AOR=3.9,95%CI:1.694,8.979),eatingleafyvegetable(AOR=0.12,95%CI:0.064,0.2
46),and taking milk with tea {AOR=2.8,95%CI:1.482,5.616 } were statistically significant with 
anemia. On the other hand, anemia is found to be independent associated factors of adverse 
perinatal outcome; individualwith anemia were 4.1 times more likely to have adverse perinatal 
outcome as compared to non-anemic (4.1,95%CI:2.609,6.405).
Conclusion and Recommendation: This study indicated that prevalence of anemia was 
moderate public health problems .And women with anemia more likely to develop adverse 
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perinatal outcome compared to their counter parts. Therefore, strengthening the provision of 
antenatal care and information communication education and behavioral change communication 
is better given attention.